Board Thread:General Discussion/@comment-25896389-20160517051356/@comment-24674051-20160518173518

Personally, I think we've seen the last of the seperation serum. Hyde used it to seperate himself from Jekyll, and Regina used to to sepearate herself from the EQ. No one else is looking to be seperated from their darkness. Rumple embraces it and loves it. Emma and Killian have accepted theirs and have found peace with themselves (Emma more than Killian). Regina, based on what was shown in Untold Story, had great difficulty accepting her darkness, and as a result could not find internal peace, which is why she chose to seperate herself. The Serum was a one time thing used for plot sake.

If anything, I could see the story take a turn to where Emma and (good) Regina, working with Hyde, develop a potion that allows for reintegration of the 2 sides. and in fact, that storyline would be worth a look, since I think that integrating inner darkness and light is a good metaphor for what people experience on a daily basis in one form or another.